HiC2Self: Self-supervised denoising for bulk and single-cell Hi-C contact maps

Alireza Karbalayghareh

Senior Research Scientist, AI/ML

My research focuses on developing universal AI models of gene regulation, capturing cis-regulation, trans-regulation, and intercellular signaling by integrating multimodal, multiomic observational, spatial, time-resolved, and perturbational data from immune cells across diverse biological contexts to understand and engineer the immune system to prevent and treat disease.