SPEN loss in DLBCL - Cancer Discovery

Our collaborative work on SPEN loss in extrafollicular diffuse large B-cell lymphoma, led by the Melnick lab, is published in Cancer Discovery.

Alireza Karbalayghareh
Alireza Karbalayghareh
Senior Research Scientist, AI/ML

My research focuses on developing universal AI models of gene regulation, capturing cis-regulation, trans-regulation, and intercellular signaling by integrating multimodal, multiomic observational, spatial, time-resolved, and perturbational data from immune cells across diverse biological contexts to understand and engineer the immune system to prevent and treat disease.