Biography
I am a Senior Research Scientist in the AI/ML group at Biohub New York. Previously, I was a Postdoctoral Research Associate in the Computational and Systems Biology program of Sloan Kettering Institute working with Dr. Christina Leslie. I received my Ph.D. in Electrical Engineering from Texas A&M University, advised by Dr. Edward R. Dougherty.
Research Interests
My research focuses on developing universal AI models of gene regulation in immune cells, capturing cis-regulation, trans-regulation, and intercellular signaling by using single-cell multiomic observational, spatial, time-resolved, and perturbational data across diverse biological contexts to understand, engineer, and reprogram the immune system to prevent and treat diseases.
PhD in Electrical Engineering, 2019
Texas A&M University
MSc in Electrical Engineering, 2014
Sharif University of Technology
BSc in Electrical Engineering, 2011
Iran University of Science and Technology
Senior Research Scientist, AI/ML
Jun. 2025–presentBiohub, New York
Postdoctoral Research Associate
Sept. 2019–Jun. 2025Memorial Sloan Kettering Cancer Center, New York
Research
DoFormer
Intervention-aware gene perturbation modeling with causal Transformers
DynaVelo
Learning multiomic velocities of single cells by latent neural ODEs
ENCODE-rE2G
An encyclopedia of enhancer-gene regulatory interactions in the human genome
GraphReg
Chromatin interaction aware gene regulatory modeling with graph attention networks
OBTL
Optimal Bayesian Transfer Learning
News
Publications
Contact
- a.karbalayghareh@biohub.org
- 615 W 131st St, New York, NY 10027
- Biohub New York